As we age, our skin naturally loses firmness and elasticity—leading to wrinkles, deeper folds (like nasolabial lines), and volume loss. While cosmetic surgery can deliver dramatic transformations, biostimulators like Radiesse® and Sculptra® offer non-surgical alternatives that are minimally invasive, natural-looking, and long-lasting. These advanced treatments are among the most sought-after anti-aging procedures today, accounting for a significant portion of non-surgical rejuvenation.
Radiesse® is an FDA-approved injectable made of calcium hydroxylapatite (CaHA)—a safe, biocompatible substance used in medicine for decades. Its smooth gel formula instantly replenishes volume while stimulating your skin's own collagen production. Sculptra®, made of poly-L-lactic acid (PLLA), works more gradually to rebuild collagen over time, providing subtle, progressive enhancement. Both biostimulators go beyond traditional fillers by addressing the underlying cause of aging—collagen loss—creating natural, lasting rejuvenation that improves facial contours, definition, and skin quality.
Biocompatible formulas: Radiesse (CaHA) and Sculptra (PLLA) safely integrate with your skin for immediate or gradual volume and long-term collagen renewal.
Customized results: Choose Radiesse for immediate smoothing or Sculptra for progressive enhancement over multiple sessions.
Gradual collagen boost: Both products act as scaffolds, stimulating your skin to produce significantly more collagen over 3–6 months.
Why Patients Choose Biostimulators Over Surgery
✓ Zero downtime – Lunchtime procedure with immediate return to activities
✓ No scarring or anesthesia risks – Non-invasive alternative to facelifts
✓ Preventative anti-aging – Early treatment slows volume loss progression
*Based on clinical studies of collagen-stimulating fillers
Initial treatment: Products integrate, creating structure while triggering fibroblast activity.
Weeks 2–4: Collagen production accelerates, reducing fine lines and improving elasticity.
Months 3+: Products gradually metabolize, leaving behind your natural collagen for results lasting 12–24 months.
Softens downturned corners of the mouth
Restores lost volume for a more youthful smile
Collagen stimulation provides long-term improvement
Fills deep smile lines between nose and mouth
Provides immediate smoothing effect
Promotes natural collagen renewal over time
Restores midface volume loss
Creates lifted, youthful contours
Maintains fullness through collagen stimulation
Reduces early signs of jowling
Enhances jawline definition
Provides structural support to prevent sagging
Sharpens and defines sagging jawlines
Creates more balanced facial proportions
Offers both instant and progressive results
Softens wrinkles and dimpling
Improves weak chin projection
Delivers natural-looking augmentation
For complete facial rejuvenation, RADIESSE pairs beautifully with Botulinum Toxin for dynamic wrinkles, thread lifts for lifting, or PRF treatments for skin quality enhancement.
Our biostimulator consultation includes a 3D facial assessment to identify areas of volume loss in your midface, jawline, or hands that would benefit most from collagen stimulation. We use visual aids to show how these unique treatments can enhance your natural contours.
You'll receive a personalized treatment plan covering:
We'll also discuss combining biostimulators with Botulinum Toxin® or PRF treatments for comprehensive facial rejuvenation when appropriate.
1. Dual-Action Rejuvenation
Customizable results: Choose Radiesse® for immediate improvement or Sculptra® for gradual enhancement
Long-term collagen boost: Stimulates your body's natural collagen production for results that improve over 3-6 months and last 12-24 months
2. Natural-Looking Enhancement
Biocompatible formulas move naturally with expressions
Avoids the "overfilled" look while restoring volume
3. Versatile Treatment Areas
Face: Smooths nasolabial folds and marionette lines
Contouring: Enhances jawline and chin projection
Overall rejuvenation: Improves skin quality and texture
4. Minimal Downtime
No recovery needed – return to activities immediately
Minimal swelling resolves within 24-48 hours
5. Customizable Results
Tailored plans for subtle or dramatic changes
Combines with Botulinum Toxin® and PRF treatments
Progressive improvement over time
Why Choose Biostimulators?
FDA-approved safety profile
Proven collagen stimulation
Long-lasting results
Expert Answers from Yeny Liscano MedSpa
Biostimulators are collagen-stimulating injectables that include Radiesse® (calcium hydroxylapatite) and Sculptra® (poly-L-lactic acid). Unlike traditional fillers, these treatments provide immediate or gradual volume while stimulating your body's natural collagen production. They work by creating a scaffolding effect under the skin that integrates with your tissue for longer-lasting results than traditional hyaluronic acid fillers.
Radiesse provides immediate volume correction plus long-term collagen stimulation, with results visible right after treatment. Sculptra works more gradually, requiring 2-3 sessions spaced 4-6 weeks apart, with results developing over several months as it stimulates your own collagen production. Radiesse typically lasts 12-18 months, while Sculptra results can last up to 24 months. Your provider will recommend the best option based on your treatment areas and desired timeline.
Ideal candidates are healthy adults experiencing moderate to severe volume loss in the midface, jawline, or hands who want natural-looking results that improve over time. During your consultation, we'll assess your skin quality and goals to determine if Radiesse® or Sculptra® is your best option. Those who are pregnant or have certain medical conditions may need alternative treatments.
The procedure typically takes 30-60 minutes depending on treatment areas and product used. We begin with cleansing and optional numbing cream, followed by precise injections. Most patients describe the discomfort as mild pinching, and you can return to normal activities immediately after with minimal downtime.
With Radiesse®, you'll notice immediate smoothing effects after treatment, with optimal results visible after about 2 weeks as swelling subsides. With Sculptra®, results develop gradually over 2-3 months as collagen production increases. The collagen-stimulating effects continue improving your skin's texture for 3-6 months. Results typically last 12-24 months - significantly longer than hyaluronic acid fillers - though this varies by individual metabolism, treatment area, and product used.
Unlike temporary hyaluronic acid fillers that simply add volume, biostimulators provide dual-action results: immediate or gradual correction plus long-term collagen stimulation. These advanced formulas create natural-looking enhancement that moves with your facial expressions and typically last twice as long as many HA fillers, making them ideal for structural contouring and overall facial rejuvenation.
Have more questions about our Miami MedSpa services?
View All FAQsWe are dedicated to providing personalized care tailored to your unique needs. Fill out the form, and one of our experts will reach out to you to schedule your consultation.